Citybound traffic is heavy on the M2 due to a crash involving a mobile crane at Macquarie Park.
One of two citybound lanes of the motorway is closed approaching Lane Cove Road.
The Lane Cove Road off-ramp is also closed.
Emergency services and traffic crews are on site.
Motorists are advised to allow additional travel time and exercise caution.
For the latest traffic information, download the Live Traffic NSW app, visit www.livetraffic.com or call 132 701.