The Snowy Mountains Highway is closed in both directions due to a truck and car crash near Old Mountain Road Walk at Talbingo.
The highway is closed between Miles Franklin Drive at Talbingo, and Link Road near Adaminaby.
Motorists are advised to avoid the area and delay their trips as there is no suitable diversion available.
Emergency services and traffic crews are attending.
For the latest traffic information, download the Live Traffic NSW app, visit www.livetraffic.com or call 132 701.